Of the five senses, smell in Western culture has gotten a bad rap. In the English language there are fewer positive equivalents for the sense of smell than there are for the other four senses. You might sniff out a deal or smell a rat but the terms for nose in our vocabulary particularly as they relate to wine are more often than not derogatory (snobby, snooty, snotty, etc.).
Although we understand the physiology of the olfactory epithelium, the organ where volatile aroma compounds are converted in to the electrochemical signals that we perceive as aromas, smell or olfaction is still largely a mystery. For example, we have 400 types of olfactory receptors but we don’t know which volatile aroma compounds activate the majority of them.